Function–Function Correlated Multi-label Protein Function Prediction over Interaction Networks
نویسندگان
چکیده
منابع مشابه
Function-Function Correlated Multi-Label Protein Function Prediction over Interaction Networks
Many previous works in protein function prediction make predictions one function at a time, fundamentally, which assumes the functional categories to be isolated. However, biological processes are highly correlated and usually intertwined together to happen at the same time; therefore, it would be beneficial to consider protein function prediction as one indivisible task and treat all the funct...
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Most of a cell’s functional processes involve interactions among proteins, and a key challenge in proteomics is to better understand these complex interaction graphs at a systems level. Because of their importance in development and disease, protein-protein interactions (PPIs) have been the subject of intense research in recent years. In addition, a greater understanding of PPIs can be achieved...
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A. Vazquez, A. Flammini, A. Maritan and A. Vespignani 1 Department of Physics, University of Notre Dame, Notre Dame, IN 46556, USA 2 International School for Advanced Studies (SISSA) and INFM, V. Beirut 2-4, 34014 Trieste, Italy 3 The Abdus Salam International Centre for Theoretical Physics, P.O. Box 586, 34100 Trieste, Italy and 4 Laboratoire de Physique Theorique (UMR du CNRS 8627), atiment 2...
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ژورنال
عنوان ژورنال: Journal of Computational Biology
سال: 2013
ISSN: 1066-5277,1557-8666
DOI: 10.1089/cmb.2012.0272